CheckMan Stock Market Overview

uniQure faces a major setback as the FDA reversed its stance on using external controls for AMT-130's approval, delaying its BLA submission. QURE's pivotal Phase 1/2 trial showed 75% slowing in cUHDRS at 36 months, but regulatory uncertainty now overshadows these results. With $694M in cash, QURE can weather a prolonged regulatory process, but AMT-130's near-term value is materially diminished.

Steel stock Cleveland-Cliffs Inc (NYSE:CLF) was last seen up 2.6% to trade at $12.35, brushing off a downgrade from KeyBanc to "sector weight" from "overweight.

Regulatory clarity unlocked AI-first Search. AI Overviews improve ad quality, not volume. Alphabet Inc. cash flow funds the transition internally.

UBS raised its rating to Buy and hiked its price target, citing growth in beauty, handbags, and Athleta.

Advanced Micro Devices (AMD) stock suffered a tumble earlier this week, after rival Intel (INTC) launched its latest AI laptop chip at the Consumer Electronics Show (CES) in Las Vegas. The security was last seen down 2.7% to trade at $204.44, on track for its fourth-straight loss, though underlying support resides at the round $200 level.

Headlines these days are full of news about armed conflicts. This naturally has investors thinking about defense stocks, an industry where valuations have soared.

A new year can bring the adoption of a new perspective, which also applies to portfolio exposure. With that, the tried-and-tested 60-40 portfolio may be best flipped by instead using a 40-60 portfolio in a year that brings more uncertainty.

The S&P 500, Dow Jones Industrial Average (Dow), and Nasdaq Composite are all stock market indexes used to measure the performance of various aspects of the U.S. stock market.

Bit Digital Inc (NASDAQ:BTBT) earned a repeat ‘Outperform' rating and $5.50 price target, according to Noble Capital Markets analysts who highlighted the company's December Ethereum treasury update and reiterated confidence in its strategic positioning. The analysts wrote that Bit Digital's latest disclosure shows continued growth in its Ethereum holdings and staking activity.

As the Google parent company edges closer to a $4 trillion market capitalization, a new bull cheers AI advantages that can keep the rally going.